Aug 5

Aug 5 Chapter Five (B) — Results and Statistics Analysis.

Preface

THIS WILL BE PUBLISHED PER CHAPTERS: PART 6/8.

During my final year of my bachelor of pharmacy, I had the joy of doing a project in pharmaceutics on topical corticosteroids. My colleague and I achieved a distinction for this project but we do admit that we can see some mistakes in our project. This project took us 6 months to accomplish and it mainly taught us about research, reading the literature and to attempt at making a pharmaceutics project. This was more of an introduction to a masters degree path and also taught us to work on our own and be supervised with an allocated supervisor. All in all, we learned a great deal and we were thankful for it.

Authors: Andréas L.P. Astier, Priyanka Naidoo

Supervisors: Professor R. Walker, Dr S.M. Khamanga

Location: Pharmaceutics Department, Rhodes University, Grahamstown, 6140, South Africa.

CHAPTER FIVE

Statistical analysis

5.7.1. T-test

5.7.1.1. Formulation 1 versus formulation 4 on day 0

5.7.1.2. Formulation 2 versus formulation 4 on day 0

5.7.1.3. Formulation 3 versus formulation 4 on day 0

5.7.1.4. Formulation 1 versus formulation 4 on day 28

5.7.1.5. Formulation 2 versus formulation 4 on day 28

5.7.1.6. Formulation 3 versus formulation 4 on day 28

Table 5.32. Spreadability statistical data significance summary

Statistically, the significant changes show that the formulation mean distance in centimetres were different compared to the standard formulation, which would be formulation 4. Formulation 2 had no significant changes throughout the whole 28 days compared to the standard and kept the ideal and wanted spreadability of the standard.